ZeClinics services strength lies on our extensive experience in zebrafish research and our permanent collaboration with several academics, imaging processing experts and other biotech companies, which allow us to perform and improve high-throughput assays to test the safety of chemical compounds with pharmaceutical, cosmetic or nutritional potential.
Long-term toxicity can be predicted from studies with early life-stages, a good reason why using zebrafish larvae in toxicology screening. We offer acute an chronic high-throughput toxicity services.
We offer ZeGlobalTox, a quick and economical tool for assessing potential toxicities in large libraries of molecules at a deep morphological and functional level early in drug development. It has the potential to reduce the number of compounds entering regulatory in vivo studies and to reduce costly late stage attrition.
In addition, we use zebrafish as biosensor for ecotoxicity. This model is a growing component of the environmental hazard assessment of chemicals and environmental samples from most different locations (cities, environment, industries, agriculture).
We also offer a growing portfolio of efficacy assays to test in zebrafish the biomedical relevance of novel compounds in the fields of oncology and neural disorders. However, our main value is our capacity to listen to your requirements and develop custom assays to test compounds in many biomedical contexts such as metabolism, anti-microbiology or other diseases (ZeCustom).
Finally, ZeClinics provides its expertise in transgenic manipulation and zebrafish biology services for generating mutant and/or knock-in lines by CRISPR/Cas9 Genome-Editing Technology (LICENCED BY THE BROAD INSTITUTE, MIT, HARVARD UNIVERSITY), and later phenotype them, in order to use them for custom drug screenings.
We are also happy to collaborate with you, when you need a partner to take promising molecules to the next level or test your research hypothesis using zebrafish.
Just tell us your biological/pharmacological question and we propose and run the best zebrafish-based scientific methodology and provide reliable results. Rare diseases, gene functions, biological pathways, drug-target interaction, drug accumulations and much more can be developed and studied in zebrafish.ASK US ABOUT ZeCUSTOM