14 Ph.D. positions are available in the framework of the Marie Curie Innovative Training Network (ITN) on Training researchers for Studying Ciliary Signalling in Development and Disease (SCilS)
Primary cilia are microtubule-based projections from the cell surface of nearly every cell in our body. In the last two decades, it has become clear that primary cilia have evolved to be key signaling hubs of the cells, as they concentrate or segregate components of major cellular signaling pathways. Dysfunctional cilia can lead to over 35 severe human genetic traits (ciliopathies) with highly heterogeneous, overlapping phenotypes, affecting as many as 1 in 400 people. We now know that humans critically depend on cilia to see, hear, smell, breathe, excrete and reproduce. Such activities require a high degree of regulation and critical feedback to ensure robustness in the development and cellular homeostasis of different tissues and organs.
SCilS training will give Early Stage Researchers (ESRs) unparalleled training opportunities in outstanding academic and industrial settings through training-by-research via individual research projects, secondments, and network-wide training sessions. All individual training and research activities have been designed to provide each ESR with the necessary broad competences in state-of-the-art academic and industrial research. The network will thereby make a career in both industry and academia attractive to the ESRs and improve their career prospects in both private and public sectors.The anticipated start date of employment is between 1 March 2020 and 1 October 2020, and is to be agreed with your supervisor. You will receive an attractive salary including mobility allowance and family allowance (if applicable) as laid down in the Horizon 2020 Marie Skłodowska-Curie actions Work Programme 2018-2020.
Applicants should be in the first 4 years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree. This is measured from the date when a degree that formally entitles you to embark on a doctorate was obtained until the start date of employment.
Applicants are willing to move to the country of the host institution of interest.
Applicants should not have resided or carried out their main activity (work, studies, etc.) in the country of the host institution of interest for more than 12 months in the 3 years immediately before the start date of employment. Short stays, such as holidays, are not taken into account.
You are proficient in written and spoken English.
You have the requested skills and experience for the Ph.D. project(s) of interest.
How to apply: Applicants must submit (see application documents)
a personal statement explaining their motivation and project interests and the contact details of 2 academic referees
an EU format CV (other formats are NOT accepted)• a form indicating the preference for one or more specific partner institute(s) and/or research project(s)
Deadline: January 15, 2020, after which we will review applications and interview candidates.
PLEASE NOTE that applications that do not meet the requirements WILL NOT BE CONSIDERED.
After the closing of the application procedure, the local supervisors will evaluate the applications for their Ph.D. project and select candidates for a face-to-face or video interview based on relevant education, scientific skills and experience, motivation and reference letters. Candidates will be asked to give a presentation during the interview. The supervisors will make a final ranking of preferred candidates for their Ph.D. project after the interviews.
Master degree in biomedical sciences, life sciences, chemistry, or computer science/mathematics.
Research experience: Previous experience in cilia/ciliopathy research is not required. Information on your research experience, related to your motivation to apply, must be included with your personal statement (see: application documents)
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie actions grant nº861329.
ZeClinics offers an exciting opportunity for a HISTOLOGY TECHNICIAN to be part of the team, whose mission is to provide an outsourcing solution for safety and efficacy screenings of novel chemical molecules using zebrafish. The prospective candidate will be service-oriented and will closely interact with ZeClinics researchers helping them in carrying out histological techniques for commercial projects. We offer work in a highly stimulating environment with state-of-the-art infrastructure, providing the successful applicant with unique opportunities to develop a competitive CV.
Holding a Laboratory Technician Bachelor’s (FP2) or Master’s degree (and equivalent) in biotechnology, biology, biochemistry, biomedical laboratory science, or a related discipline will be necessary. Holding experience in zebrafish biology or genetics and genomics is just a plus.
Technical skills required
Proved experience in preparation of animal tissues for microscopy (fixation, inclusion in paraffin, microtomy, cryotomy) and in-depth knowledge of specific stains for samples of different nature.
Knowledge of immunohistochemistry and in situ hybridization techniques.
A minimum of two years of previous experience in the area of histology is required (preparation of samples for inclusion in paraffin, cuts with a microtome, cryostat, immunohistochemistry techniques).
Experience with chemicals administration, other biochemical, molecular, or cellular techniques, microinjection, and zebrafish biology or husbandry, will be very much appreciated but will not be mandatory.
Ability to work independently and also to interact with collaborators of the lab and the core facilities.
FELASA certification to perform scientific experiments with animals (Level B or C) will be a plus.
Able to understand and speak English
Duration: Work and Service
Estimated annual gross salary: According to experience
Starting date: February
All applications can be done through our STAFF RECRUITMENT website form and must include: