GRANTS

InnoTCM – Innovative Ways of Profiling Traditional Chinese Medicinal Herb Extracts Through Zebrafish

The concept of the InnoTCM project is to apply an innovative approach of profiling the TCM herb extracts by using Zebrafish as a model organism in High Throughput Screening (HTS) manner.

completed
Papers

In silico and in vivo models for Qatari-specific classical homocystinuria as basis for development of novel therapies.

Valeria Di Giacomo, Senior R&D Researcher in ZeClinics, presents a new paper in collaboration with Qatar University.

GRANTS

CARDIOREG – Biomarkers and lead molecules for heart regeneration therapies

We aim to implement cardiac injury models in zebrafish and to use them to identify genes involved in heart regeneration, with a focus on genes impairing cardiomyocyte dedifferentiation/proliferation.

completed
ZeClinics Resveratrol Papers

Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases

The team led by Dr. Morales has synthesized alkylated resveratrol prodrugs to improve antioxidant and anti-inflammatory properties.

GRANTS

ZF-Glioma – Generation of transgenic zebrafish expressing human tyrosine kinase mutants as human glioma (brain cancer) models

ZF-Glioma's aim was to model human glioma (brain cancer) in zebrafish to screen for tyrosine kinase inhibitors (TKIs) with the potential to treat this devastating disease.

completed
Valeria_ZeClinics Papers

Valeria Di Giacomo, R&D Scientist at ZeClinics, has just published an impressive review article in FRONTIERS

They explore the benefits of CRISPR/Cas9 to establish innovative zebrafish models to enhance knowledge of the visual cycle.

Papers

Enhancing understanding visual cycle applying crispr/cas9 gene editing zebrafish

They explore the benefits of CRISPR/Cas9 to establish innovative zebrafish models to enhance knowledge of the visual cycle.

Papers

An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System

They establish a mechanism that may represent a general principle for neural network assembly in vertebrate species and across different brain areas.

NEURON - Vincenzo Di Donato, R&D Scientist at ZeClinics, has just published an impressive paper Papers

Vincenzo Di Donato, R&D Scientist at ZeClinics, has just published an impressive paper in NEURON

An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System.

Papers

Paper published: “ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish”

Our article "ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish" has been published in IJMS

GRANTS

ZeCardio – Cardiotoxicity High-throughput screening (HTS) with zebrafish embryo

Within this project ZeClinics developed ZeCardio®, a unique, fully automated, robotic and software-driven cardiovascular screening platform.

completed
GRANTS

ZePharma – Process development and automation for the preclinical phase of new drug discovery

The objective of the project is to analyze libraries of molecules provided by collaborating entities with a view to discovering molecules with cardioprotective and anti-tumor therapeutic actions.

completed
GRANTS

STEM ZeOncoTest – Diagnostic method to assess the effectiveness of antitumor drugs

The STEM-ZeOncoTest is an innovative and versatile product for oncological diagnosis that offers a quick and economical solution for making decisions about the treatment of therapy.

completed
GRANTS

ZeGlobalTox – multi-organ toxicity testing in zebrafish

ZeGlobalTox is an innovative safety test able to reduce the number of used animals, experimental time and R&D costs during drug discovery.

completed