papers

An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System

They establish a mechanism that may represent a general principle for neural network assembly in vertebrate species and across different brain areas.

papers

ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish

ZeGlobalTox is an innovative assay that sequentially integrates in vivo cardio-, neuro-, and hepatotoxicity assessment in the same animal, thus impacting strongly in the 3Rs principles.

GRANTS

ZeCardio – Cardiotoxicity High-throughput screening (HTS) with zebrafish embryo

Within this project ZeClinics developed ZeCardio®, a unique, fully automated, robotic and software-driven cardiovascular screening platform.

completed
GRANTS

ZePharma – Process development and automation for the preclinical phase of new drug discovery

The objective of the project is to analyze libraries of molecules provided by collaborating entities with a view to discovering molecules with cardioprotective and anti-tumor therapeutic actions.

completed
GRANTS

STEM ZeOncoTest – Diagnostic method to assess the effectiveness of antitumor drugs

The STEM-ZeOncoTest is an innovative and versatile product for oncological diagnosis that offers a quick and economical solution for making decisions about the treatment of therapy.

completed
papers

Switching to zebrafish neurobehavioral models: The obsessive-compulsive disorder paradigm

We propose zebrafish as an appropriate animal model to streamline the pipeline of gene functional validation of Obsessive-compulsive disorder (OCD) risk associated genes.

GRANTS

ZeGlobalTox – multi-organ toxicity testing in zebrafish

ZeGlobalTox is an innovative safety test able to reduce the number of used animals, experimental time and R&D costs during drug discovery.

completed