Otolaryngology

A rapid and quantitative functional study for hearing loss evaluation. Zebrafish conserves the sensory system external, being the same cell types as the human inner ear, called hair cells.  These detect local water displacements and vibration. The accessibility to the hair cells (HC) on the lateral line, and the transparency of the model, facilitates the visualization and study of novel compounds’ efficacy.

At ZeClinics, we provide solutions for the evaluation of novel compound’s capacity to enhance the regeneration of hair cells or prevent the injury of these. The evaluation is based on the HCs of four different posterior lateral line of neuromasts in both sides of the individuals. The increased number of ex-novo HC in these neuromasts will indicate the capacity of regeneration or protection of the tested drug.


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