POSTERS

Zebrafish, a novel key player for human risk assessment: latest advances on developmental neurotoxicity from an international consortium.

ZeClinics_Poster_Zebrafish POSTERS
POSTERS

Zebrafish-based high throughput platform for human developmental toxicity assessment

ZeClinics_Poster_Zebrafish-based-high-throughput-platform-for-human-developmental-toxicity-assessment POSTERS
POSTERS

A novel medium-throughput platform for target validation of regulators of cardiac regeneration in zebrafish larvae

Weinstein-poster-rev-page-0001 POSTERS
papers

Implementation of Zebrafish Ontologies for Toxicology Screening

The NTP’s SEAZIT undertook a collaborative exercise to evaluate how the application of standardized phenotype terminology improved data consistency.

papers

Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration

We demonstrate the highly conserved nature of NGF canonical pathway in zebrafish and thus support the use of zebrafish models for testing new compounds with potential retinal regenerative properties.

GRANTS

ZeBYTE – Platform to predict the effect of drugs based on the use of zebrafish and artificial intelligence

ZeBYTE aims at using artificial intelligence technologies along the whole target discovery process.

ongoing
POSTERS

Unraveling the role of the primary cilium in heart regeneration

poster_katerina POSTERS
GRANTS

REMODEL- pREcise gene delivery for advanced disease MODELing

A cutting-edge gene-editing platform to generate complex disease models to test innovative therapeutic approaches.

ongoing
POSTERS

High-throughput and integrative approaches for quality control of Cas9 variants

Poster-IZFC-2021 POSTERS
GRANTS

ROBO-FISH – Automated high-throughput oncology drug screening in zebrafish using robotics and AI

The ROBO-FISH consortium will develop and validate injection and imaging robots to automate oncology drug screening in zebrafish to mimic human disease.

ongoing
POSTERS

Morphometric analysis in zebrafish embryos to predict teratogenicity and modes of action in mammals

Zeclinics-Poster-SOT2021 POSTERS
POSTERS

ZeGenesis: an innovative CRISPR/Cas9-based platform to boost target and drug discovery in zebrafish

poster_SLAS_FDS POSTERS
GRANTS

CARDIOMYO – An integrated HTS platform for the discovery of new therapeutics against cardiomyopathies

CARDIOMYO combines three complementary approaches: 1) high content phenotypic in vitro cardiac assays 2) a novel in vivo cardiovascular phenotyping using zebrafish and 3) drug discovery chemistry

ongoing
papers

Morphometric analysis of developing zebrafish embryos allows predicting teratogenicity modes of action in higher vertebrates

Zebrafish teratogenicity predictivity shown here reinforces the possibility of applying powerful mechanistic approaches.

papers

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function

The data presented contribute to delineate GRIN PTVs genotype-phenotype association and GRIN variants stratification

GRANTS

NanoDIRE-CT – Use of nanobodies for targeted therapy against tumor stem cells

Our purpose is to isolate nanobodies that bind cancer stemm cells and have a direct cytotoxic effect on them, or could act as carriers of cytotoxic drugs specifically towards them.

ongoing