papers

ZebraReg—a novel platform for discovering regulators of cardiac regeneration using zebrafish

A powerful tool poised to streamline the target validation of novel gene regulators for regeneration and unlock new drug therapies aimed at heart regeneration post-myocardial infarction.

papers

A Zebrafish-Based Platform for High-Throughput Epilepsy Modeling and Drug Screening in F0

The new zebrafish-based high-throughput platform allows the generation of F0 knockout models for a rapid screening of neuroactive compounds.

papers

Toward the Use of Novel Alternative Methods in Epilepsy Modeling and Drug Discovery

We explore animal alternatives, particularly zebrafish larval models, along with advanced Crispr/Cas9 techniques, streamlining epilepsy modeling and antiepileptic drug trials.

GRANTS

VIDEC (Visualizing Death Inducing Protein Complexes)

The Research network aims to develope tools for visualizing cell death to enhance treatments and identify chemical hazards.

ongoing
GRANTS

Parkinson’s drug development through AI and massive compound screening

ZeClinics joins AseBio, Celtarys Research, and USC-Biofarma in a groundbreaking €147,000 project using AI and compound screening to develop new drugs for Parkinson's.

completed
GRANTS

ZeNeuroid: Human-based Neural Organoid Network for Parkison Drug Discovery

The project takes advantage of patient-derived iPSCs and CRISPR-edited human iPSCs to create a Parkinson Disease neuronal disease model.

ongoing
GRANTS

ZeNeuroid: Human-based Neural Organoid Network for Drug Discovery

The project will use patient derived-iPSC and CRISPR-edited human IPSC to develop a novel three-dimensional microfluidic system for drug discovery.

ongoing
POSTERS

Increasing predictivity of compound multi-organ toxicity through high-throughput zebrafish assays

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POSTERS

A novel platform for unraveling the role of the primary cilium in heart regeneration

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GRANTS

EdiGenT – New Prime Editing and non-viral delivery strategies for Gene Therapy

The EdiGenT consortium will work to develop a new generation of more efficient gene correction tools based on the CRISPR/Cas9 system, and non-viral delivery strategies for gene therapy.

ongoing
POSTERS

Zebrafish, a novel key player for human risk assessment: latest advances on developmental neurotoxicity from an international consortium.

ZeClinics_Poster_Zebrafish POSTERS
POSTERS

Zebrafish-based high throughput platform for human developmental toxicity assessment

ZeClinics_Poster_Zebrafish-based-high-throughput-platform-for-human-developmental-toxicity-assessment POSTERS
POSTERS

A novel medium-throughput platform for target validation of regulators of cardiac regeneration in zebrafish larvae

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papers

Implementation of Zebrafish Ontologies for Toxicology Screening

The NTP’s SEAZIT undertook a collaborative exercise to evaluate how the application of standardized phenotype terminology improved data consistency.

papers

Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration

We demonstrate the highly conserved nature of NGF canonical pathway in zebrafish and thus support the use of zebrafish models for testing new compounds with potential retinal regenerative properties.

GRANTS

Kit Digital

Eleva Group has assisted ZeClinics in the installation of a Customer Relationship Management (CRM).

completed