BY OUR PLATFORMS
BY THERAPEUTIC AREA
BY RESEARCH STAGE
01 December 2020 - 30 November 2023
CARDIOMYO combines three complementary approaches: 1) high content phenotypic in vitro cardiac assays 2) a novel in vivo cardiovascular phenotyping using zebrafish and 3) drug discovery chemistry
23 November 2020
Zebrafish teratogenicity predictivity shown here reinforces the possibility of applying powerful mechanistic approaches.
10 October 2020
The data presented contribute to delineate GRIN PTVs genotype-phenotype association and GRIN variants stratification
01 September 2020 - 31 August 2023
Our purpose is to isolate nanobodies that bind cancer stemm cells and have a direct cytotoxic effect on them, or could act as carriers of cytotoxic drugs specifically towards them.
28 May 2020
We propose that zebrafish, with the use of CRISPR/Cas9 tools, could streamline functional genomic processes to bring biologically relevant knowledge on diseases.
01 January 2020 - 31 December 2024
REANIMA aims to deliver new therapies for heart regeneration, thereby reverting the conditions that lead to heart failure.
01 January 2020 - 31 December 2023
SCilS is training a new generation of scientists to characterise ciliopathies, an increasingly important and diverse class of inherited diseases.
01 October 2019 - 30 September 2023
The EU-funded ZENITH project is preparing a new generation of scientists for interdisciplinary collaboration on pressing neuroscience challenges utilising the zebrafish model system.
05 September 2019
26 August 2019
05 August 2019
Our analysis with zebrafish yields similar predictive performance as previous validation meta-studies performed with dogs, the standard regulatory preclinical model.
04 July 2019
Functional experiments demonstrated the pivotal role of Yap/Taz-TEAD signaling in maintaining progenitor features in the hindbrain boundary cell population.
05 June 2019
01 June 2019 - 31 May 2021
We propose the development of a high-throughput preclinical platform using the zebrafish model to find suitable treatments for heart regeneration after ischemia.
22 May 2019
26 February 2019
These data strongly support the role of SLC9A3R1 gene in the pathogenesis of ARHL.
Please leave your details in the form below.