Transgenic Animal Models In Biomedical Research Genetics

Transgenic Animals in Biomedical Research and Drug Discovery

Transgenic Animals Meaning + Application Examples

two knockout applications gene inactivation vs exon deletion Genetics

Two CRISPR/Cas9 Gene Knockout Methods

Two Applications of CRISPR/Cas9 Gene Knockout

zebrafish a key asset in ophthalmology drug discovery Ophthalmology

Zebrafish: A key asset in ophthalmology drug discovery

Readily assess visual function in a live organism


HDR vs NHEJ in CRISPR Gene Editing

Understanding DNA Repair Pathways


Fast Gene Target Validation & Drug Screening All In One

Harness the potential of our new Zebrafish-Based Platform for High-Throughput Gene Target Validation and Drug Screening in F0


CRISPR Knockouts vs Knockins

The use of target gene-editing in preclinical research


Prime editing, a step beyond CRISPR

The most precise CRISPR to date turns the genetic scissors into a Swiss army knife 

Drug discovery

The future of animal testing 

The United States approves technological alternatives to reduce animal testing

CRISPR-the-genetic-scissors Genetics

CRISPR: the genetic scissors

What is CRISPR technology and how can change our lives?


What is gene editing and how does it work?

Gene editing enables scientists to alter the sequence of genes by adding, replacing, or removing certain DNA segments.


Genetic inheritance and gene mutations 

How does genetic information pass down through generations and what errors can occur?


The genetic code

The correspondence between two biological languages


The central dogma of molecular biology

What is the relationship between DNA, RNA and proteins?

Zebrafish model organism

Zebrafish larvae as a New Alternative Methodology (NAM) for the assessment of compounds’ teratogenicity

Combining a zebrafish-based high throughput platform with artificial intelligence for human developmental toxicity assessment.

Zebrafish model organism

Can Zebrafish Testing Help Bring Your Drug To Market?

Zebrafish contribution to drug development reaching clinical stages

AI-in-drug-Discovery Drug discovery

How Artificial Intelligence Can Unlock Cures for Current and Future Diseases?

AI can address many challenges and limitations in traditional R&D and offer value in drug discovery in multiple ways.

zebrafish-embryos Zebrafish model organism

Regulatory Compliance and The Zebrafish Model (Part II)

Zebrafish for regulatory purposes in ecotoxicology and safety pharmacology

Zebrafish model organism

Regulatory Compliance and The Zebrafish Model (Part I)

New trends and updated availability for zebrafish studies in EU and US

In-vivo-epilepsy-research Drug discovery

Fishing for innovative alternatives for modeling epilepsy

Why zebrafish can pave the way for investigating epilepsy’s etiology and screening new anti-seizure drugs

differences-between-in-vitro-in-vivo-in-silico assays- Drug discovery

Differences between in vitro, in vivo and in silico assays in preclinical research

How to choose which type of experiment is best-suited for my research?


How Environmental Chemicals can Alter the Endocrine System… and What Zebrafish can do about it!

Use of biomarkers in endocrine disruption compounds screening and testing with zebrafish


Zebrafish on the Move Towards Eye Disorders Research

Leveraging zebrafish to study Age-related Macular Degeneration


Tackling a pandemic with Zebrafish: Obesity and Non-Alcoholic Liver Disease

The emerging use of zebrafish to model metabolic diseases

Zebrafish model organism

Zebrafish as a Translatable Model System

Are zebrafish suitable for human drug discovery?

regulatory_status_of_zebrafish Zebrafish model organism

Zebrafish Make a Splash in Animal Experimentation

The regulatory status of zebrafish as an alternative preclinical model.

zebrafish-larvae Zebrafish model organism

How Automation and Optimization Help us do Better Science

In ZeClinics we bet on emerging technologies to scale our solutions.

zebrafish-pharmacologial-disease-model CNS

What can you Learn from a Neuro-Pharmacological Disease Model?

Zebrafish represents a key tool to boost drug discovery by enabling phenotypic screening approach in pharmacological-based disease models.

screening-toxicity-with-zebrafish Toxicology

Dozens of Compounds with Unknown Toxicity Profiles in your Hands: Why Entrust the Screening to Zebrafish?

From challenge to knowledge: the outstanding performance of zebrafish in predicting toxicity.

zebrafish-genome Genetics

Can you Play with the Zebrafish Genome for Drug Discovery?

ZeClinics can do it by using different genome editing approaches.

Larvae zebrafish at ZeClinics Zebrafish model organism

R&D: What does ZeClinics do?

ZeClinics laboratory R&D efforts are mainly divided in the development of three research platforms including a number of research areas.

zebrafish Zebrafish model organism

The Zebrafish Model: A Powerful Tool for Answering Complex Questions

We knew the model was brilliant for academic research. Would it be as good for modeling human disease and discovering new drugs in an industrial setting?