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Zebrafish in Early Drug Discovery: Advancing Pharma Research Uncategorized

Zebrafish in Early Drug Discovery: Advancing Pharma Research

Accelerating Drug Development with Zebrafish Models

Zebrafish Model Organism All You Need To Know Zebrafish model organism

Zebrafish Model Organism: All You Need To Know

Exploring the Benefits of Zebrafish Model in Modern Research

High-Content Screening Principles, Techniques, and Applications Zebrafish model organism

High-Content Screening: Principles, Techniques, and Applications

Advancing Drug Discovery with Zebrafish High-Content Screening

Zebrafish and the 3Rs A Modern Approach to Ethical and Efficient Research Zebrafish model organism

Zebrafish and the 3Rs: A Modern Approach to Ethical and Efficient Research

Leveraging Zebrafish for Reduction, Refinement, and Replacement in Preclinical Studies

Fluorescent Screening of Zebrafish Injected Embryos Zebrafish model organism

Fluorescent Screening of Zebrafish Injected Embryos

Identifying Successfully Injected Embryos With Fluorescence

Zebrafish Embryo Microinjection Technique Zebrafish model organism

Zebrafish Embryo Microinjection Technique

How To Do A Microinjection of Zebrafish Embryos?

Zebrafish Reproduction and Breeding Strategies Zebrafish model organism

Zebrafish Reproduction and Breeding Strategies

Proven Techniques for Successful Zebrafish Reproduction and Embryo Collection

Genetic Similarity Between Zebrafish and Humans Zebrafish model organism

Genetic Similarity Between Zebrafish and Humans

Understanding Shared Genes and Their Impact on Human Medicine

Zebrafish Feeding Live vs. Dry Food Strategies Zebrafish model organism

Zebrafish Feeding Guide: Live vs. Dry Food

What Does Zebrafish Eat? Balancing Nutrition and Convenience with Live and Dry Food

Cleaning and Disinfecting Zebrafish Tanks Zebrafish model organism

Cleaning and Disinfecting Zebrafish Tanks

Essential Zebrafish Husbandry Practices for Effective Tank Cleaning and Disinfection

Best Practices for Zebrafish Husbandry: Monitoring Health and Maintaining Rack Systems Zebrafish model organism

Tracking Zebrafish Health

Best Practices for Zebrafish Husbandry: Monitoring Health and Maintaining Rack Systems

Optimizing Zebrafish Care: Maintaining and Scaling Colonies Zebrafish model organism

Optimizing Zebrafish Care: Maintaining and Scaling Colonies

Best Practices for Long-Term Zebrafish Care and Husbandry

Guide to Establishing Zebrafish Colonies Zebrafish model organism

Establishing Zebrafish Colonies

A Step-by-Step Guide to Establishing a Thriving Zebrafish Colony

Maintaining Water Quality in Zebrafish Tanks Zebrafish model organism

Maintaining Water Quality in Zebrafish Tanks

Essential Water Quality Tips for Healthy and Thriving Zebrafish

Optimal Conditions for Zebrafish Husbandry Zebrafish model organism

Optimal Conditions for Zebrafish Husbandry

Temperature, pH, Conductivity and Density Guidelines for Zebrafish Husbandry

zebrafish diet, behavior and lifecycle Zebrafish model organism

Insights into the Diet, Behavior, and Lifecycle of Zebrafish (Danio rerio)

Understanding Zebrafish Biology and Behavior in Research

Zebrafish model organism

The History of Zebrafish as a Research Model Organism

From Ornamental Fish to a Cornerstone of Scientific Discovery

Zebrafish Models: A Game Changer in Drug Discovery Drug discovery

Zebrafish Models: A Game Changer in Drug Discovery

Discover how zebrafish accelerate early-stage screening, enhance predictive insights, and reduce costs in drug development

Dealing With The Challenges Of Drug Discovery Drug discovery

Dealing With The Challenges Of Drug Discovery

Is the Traditional Drug Discovery Process Holding Back Your Pipeline?

AI-Role-in-Transforming-Drug-Discovery_ZeClinics Drug discovery

AI’s Role in Transforming Drug Discovery: A New Frontier

The Impact of AI on Pipelines, Productivity, and Clinical Success

Drug discovery

Data Science in the Drug Discovery Industry

How Does ZeClinics Take Advantage of Data Science?

Drug discovery

Knowledge Graphs for Drug Discovery: Transforming Target Identification and Biomedical Data Integration

Leveraging Relationships in Knowledge Graphs to Enhance Drug Discovery and Target Identification

common-error-in-zebrafish-genetic-model-generation Genetics

Common Errors in Zebrafish Genetic Model Generation

Key Mistakes to Avoid for Successful Zebrafish Genetic Modeling

CRISPR vs Tol2 Genetics

CRISPR/Cas9 vs. Tol2 Techniques for Zebrafish Genomic Manipulation

Evaluating Methods for Precision and Efficiency in Genetic Engineering

Transgenic Animal Models In Biomedical Research Genetics

Transgenic Animals in Biomedical Research and Drug Discovery

Transgenic Animals Meaning + Application Examples

two knockout applications gene inactivation vs exon deletion Genetics

Two CRISPR/Cas9 Gene Knockout Methods

Two Applications of CRISPR/Cas9 Gene Knockout

zebrafish a key asset in ophthalmology drug discovery Drug discovery

Zebrafish: A key asset in ophthalmology drug discovery

Readily assess visual function in a live organism

Genetics

HDR vs NHEJ in CRISPR Gene Editing

Understanding DNA Repair Pathways

Drug discovery

Fast Gene Target Validation & Drug Screening All In One

Harness the potential of our new Zebrafish-Based Platform for High-Throughput Gene Target Validation and Drug Screening in F0

Genetics

CRISPR Knockouts vs Knockins

The use of target gene-editing in preclinical research

Genetics

Prime editing, a step beyond CRISPR

The most precise CRISPR to date turns the genetic scissors into a Swiss army knife 

Drug discovery

The future of animal testing 

The United States approves technological alternatives to reduce animal testing

CRISPR-the-genetic-scissors Genetics

CRISPR Cas9: The Genetic Scissors

What is CRISPR technology and how can change our lives?

Genetics

What is gene editing and how does it work?

Gene editing enables scientists to alter the sequence of genes by adding, replacing, or removing certain DNA segments.

Genetics

Genetic inheritance and gene mutations 

How does genetic information pass down through generations and what errors can occur?

Genetics

The genetic code

The correspondence between two biological languages

Genetics

The central dogma of molecular biology

What is the relationship between DNA, RNA and proteins?

Zebrafish model organism

Zebrafish larvae as a New Alternative Methodology (NAM) for the assessment of compounds’ teratogenicity

Combining a zebrafish-based high throughput platform with artificial intelligence for human developmental toxicity assessment.

Zebrafish model organism

Can Zebrafish Testing Help Bring Your Drug To Market?

Zebrafish contribution to drug development reaching clinical stages

AI-in-drug-Discovery Drug discovery

How Artificial Intelligence Can Unlock Cures for Current and Future Diseases?

AI can address many challenges and limitations in traditional R&D and offer value in drug discovery in multiple ways.

zebrafish-embryos Zebrafish model organism

Regulatory Compliance and The Zebrafish Model (Part II)

Zebrafish for regulatory purposes in ecotoxicology and safety pharmacology

Zebrafish model organism

Regulatory Compliance and The Zebrafish Model (Part I)

New trends and updated availability for zebrafish studies in EU and US

In-vivo-epilepsy-research CNS

Fishing for innovative alternatives for modeling epilepsy

Why zebrafish can pave the way for investigating epilepsy’s etiology and screening new anti-seizure drugs

differences-between-in-vitro-in-vivo-in-silico assays- Drug discovery

Differences between in vitro, in vivo and in silico assays in preclinical research

How to choose which type of experiment is best-suited for my research?

Toxicology

How Environmental Chemicals can Alter the Endocrine System… and What Zebrafish can do about it!

Use of biomarkers in endocrine disruption compounds screening and testing with zebrafish

Ophthalmology

Zebrafish on the Move Towards Eye Disorders Research

Leveraging zebrafish to study Age-related Macular Degeneration

Drug discovery

Tackling a pandemic with Zebrafish: Obesity and Non-Alcoholic Liver Disease

The emerging use of zebrafish to model metabolic diseases

Drug discovery

Zebrafish as a Translatable Model System

Are zebrafish suitable for human drug discovery?

regulatory_status_of_zebrafish Zebrafish model organism

Zebrafish Make a Splash in Animal Experimentation

The regulatory status of zebrafish as an alternative preclinical model.

zebrafish-larvae Toxicology

How Automation and Optimization Help us do Better Science

In ZeClinics we bet on emerging technologies to scale our solutions.

zebrafish-pharmacologial-disease-model Drug discovery

What can you Learn from a Neuro-Pharmacological Disease Model?

Zebrafish represents a key tool to boost drug discovery by enabling phenotypic screening approach in pharmacological-based disease models.

screening-toxicity-with-zebrafish Toxicology

Dozens of Compounds with Unknown Toxicity Profiles in your Hands: Why Entrust the Screening to Zebrafish?

From challenge to knowledge: the outstanding performance of zebrafish in predicting toxicity.

zebrafish-genome Drug discovery

Can you Play with the Zebrafish Genome for Drug Discovery?

ZeClinics can do it by using different genome editing approaches.

Larvae zebrafish at ZeClinics Zebrafish model organism

R&D: What does ZeClinics do?

ZeClinics laboratory R&D efforts are mainly divided in the development of three research platforms including a number of research areas.

zebrafish Drug discovery

The Zebrafish Model: A Powerful Tool for Answering Complex Questions

We knew the model was brilliant for academic research. Would it be as good for modeling human disease and discovering new drugs in an industrial setting?