Chronic pain is a major biomedical and social problem, and its management remains a critical unmet need. Progress depends on both new analgesic therapies and better experimental models. Mammalian ones have long dominated nociception and pain research, but there is increasing evidence that comparable processes exist in fish. The zebrafish is already well established in […]

What Is Bioavailability Testing and Why It Matters in Early Drug Development Bioavailability describes the rate and extent to which an active substance reaches the targeted location in the body, usually the bloodstream, and becomes available to exert its effect. In short, it answers one specific question: what fraction of the administered dose enters the […]

Improve translatability in preclinical research using predictive in vivo models to reduce clinical failure and strengthen early drug development decisions.

High-throughput screening in early drug discovery: when to integrate in vivo models to improve candidate selection and reduce preclinical risk.

How to validate AI-driven drug discovery predictions using zebrafish models with in vivo precision, speed, and biological insight.

Good Laboratory Practices (GLP) ensure reliable preclinical research, meet FDA standards, and strengthen data integrity in drug development.

Clinical trial phases and FDA approval in drug development. Understand timelines, phase differences, and key regulatory milestones in one clear guide.

Developmental Toxicity of PROTACs: Explore in vivo screening strategies, safety concerns, and regulatory insights to support safer drug development.

Zebrafish toxicity screening helps accelerate drug discovery with early safety insights. Explore 3 fast, cost-effective strategies to de-risk compounds.

Exploring how zebrafish models accelerate neurological drug discovery through high-throughput screening and in vivo insights

How zebrafish enhance lead optimization, ADME prediction, and drug discovery efficiency in early-stage development.

Learn how zebrafish revolutionize pharmaceutical toxicology by enabling high-throughput environmental and human risk assessments.

Learn about environmental risk assessment (ERA) for medicinal products, including PBT/vPvB evaluations and the role of zebrafish in them.

Developmental toxicity screening using zebrafish offers a predictive, ethical, and cost-effective in vivo model aligned with ICH S5 (R3) standards.

Reproductive toxicity testing with zebrafish provides fast, predictive insights for early-stage drug development aligned with ICH guidelines.

Explore non-clinical safety assessments for new drugs, from ICH guidelines to zebrafish models in preclinical toxicology.

How zebrafish in vivo models enhance target validation in drug discovery and support early-stage drug development.

Zebrafish models enhance hit-to-lead optimization, accelerating early drug development with high-throughput screening.

Optimize drug discovery pipelines with zebrafish high-throughput screening. Discover automation, robotics & phenotypic screening solutions.

The Drug Discovery and Development Process: Context and Functions

Exploring how zebrafish screening transformed cardiomyopathy drug development, reducing costs and accelerating timelines

Accelerating Drug Development with Zebrafish Models

Advancing Drug Discovery with Zebrafish High-Content Screening

Discover how zebrafish accelerate early-stage screening, enhance predictive insights, and reduce costs in drug development

Is the Traditional Drug Discovery Process Holding Back Your Pipeline?

The Impact of AI on Pipelines, Productivity, and Clinical Success

How Does ZeClinics Take Advantage of Data Science?

Leveraging Relationships in Knowledge Graphs to Enhance Drug Discovery and Target Identification

Readily assess visual function in a live organism

Harness the potential of our new Zebrafish-Based Platform for High-Throughput Gene Target Validation and Drug Screening in F0

The United States approves technological alternatives to reduce animal testing

Zebrafish contribution to drug development reaching clinical stages

AI can address many challenges and limitations in traditional R&D and offer value in drug discovery in multiple ways.

Why zebrafish can pave the way for investigating epilepsy’s etiology and screening new anti-seizure drugs

How to choose which type of experiment is best-suited for my research?

Leveraging zebrafish to study Age-related Macular Degeneration

The emerging use of zebrafish to model metabolic diseases

Are zebrafish suitable for human drug discovery?

Zebrafish represents a key tool to boost drug discovery by enabling phenotypic screening approach in pharmacological-based disease models.

ZeClinics can do it by using different genome editing approaches.

ZeClinics laboratory R&D efforts are mainly divided in the development of three research platforms including a number of research areas.

We knew the model was brilliant for academic research. Would it be as good for modeling human disease and discovering new drugs in an industrial setting?